Both the MS Zaandam and MS Rotterdam have docked in Port Everglades, Florida, after weeks at sea.
The Holland America Line vessels, which have been hard hit by the coronavirus pandemic, arrived following the intervention of United States president Donald Trump.
A British man was among four people who died on Zaandam.
The vessel was carrying hundreds passengers when it set off a South America cruise from Buenos Aires to San Antonio on March 7th.
Failed attempts were made to disembark guests in Chile on March 15th and at other ports along its route to the United States, before eventual arrival in Florida.
A total of 107 passengers – 90 on Zaandam and 17 on Rotterdam – and 143 crew on Zaandam have presented with influenza-like symptoms since March 22nd.
The situation is thought to have deteriorated further in the interim.
Passengers fit to travel amid guidelines from the US centres for disease control and prevention were allowed off the ships in Florida after clearance was agreed with authorities.
They will be health screened and also cleared for entry by US customs and border protection.
Holland American Line president, Orlando Ashford, said: “These travellers could have been any one of us or our families, unexpectedly caught in the middle…